A sickle cell anaemia patient

Are you a sickle cell anaemia patient and wondering on how to stay healthy? Bother no more! Read this article to know more.

SICKLE CELL ANEMIA is an inherited genetic disease of the blood’s hemoglobin,  a component of the red blood cells.

A group of disorders that cause red blood cells to become disformed and break down.

With sickle cell disease, an inherited group of disorders, red blood cells twist into a sickle shape. The cells die early, leaving a shortage of healthy red blood cells (sickle cell anaemia) and can block blood flow causing pain (sickle cell crisis).

Sickle cell anemia is the result of the change of a single amino acid in the protein sequence hemoglobin. This change involves the substitution of valine which is a non-polar for glutamic acid which is also polar.

Two genes for the sickle hemoglobin must be inherited from one’s parents in order to have the disease. A person who receives a gene for sickle cell disease from one parent and a normal gene from the other has a condition called “sickle cell trait.” Sickle cell trait produces no symptoms or problems for most people.

Hemoglobin is responsible for carrying oxygen from the lungs to the cells. In an individual with sickle cell anemia, the defective hemoglobin molecules clump together, causing the red blood cells assume a sickle shape, hence the name. 

These abnormal cells have trouble squeezing through small blood vessel, causing oxygen depletion in organs and extremities along with episodes of pain. 

These sickle cells also have a much shorter lifetime in the body, leaving the individual with chronic anemia. 

Healthy cell and a sickle cell anaemia

SYMPTOMS

Pains in the joints

Pains can be sudden in the chest

Also Whole body dizziness, fatigue, low oxygen in the body, or malais

Inability to make concentrated or dilute urine or blood in urine

Hemolytic anemia, developmental delays, jaundice, pale skin, sausage digit, or shortness of breath is also common in some patients.

TREATMENT

Treatment can help, but this condition can’t be cured

Requires a medical diagnosis

Lab tests or imaging always required

Chronic: can last for years or maybe for lifelong.

Treatments include medication.

Blood transfusions and rarely a bone-marrow transplant.

Device therapy

Patient-controlled analgesia

Medications

Narcotic, Chemotherapy, Vitamin and Blood transfusion

POSSIBLE CURE

Stem cell or bone marrow transplants are the only cure for sickle cell disease, but they’re not done very often because of the significant risks involved.

Stem cells are special cells produced by bone marrow, a spongy tissue found in the centre of some bones. They can turn into different types of blood cells.

How to stay healthy as A Sickle cell Anaemia Patient

1. Have a pain management plan: Take your drugs and follow the plans prescribed by your Doctor.

2.Prevent Early Childhood infection by proving them with doses of the prescribed antibiotics.

3.Prevent dehydration

Drink water and other fluids. Drink enough so that your urine is light yellow or clear like water. Drink extra fluids before, during, and after exertion and when in the heat.

Sickle cell in Blood vessels

Drink plenty of fluid if you have a fever or infection. Children should keep a water bottle with them during school, play, and outings.

4. Limit alcohol intake. Alcohol use can lead to dehydration.

  • Drink plenty of fluids before, during, and after exercise. Dehydration can cause cells to sickle.
  • Get regular rest breaks during vigorous exercise.
  • Stay warm. Exposure to cold air, wind, and water can trigger a sickle cell crisis. Dress children in warm layers of clothing for cold-weather activities. Avoid swimming and playing in cold water.

5.Don’t smoke

6.Stay warm in cold. Weather period.

Good Health is the key to every endeavor to the success of our aim. Let’s take good care of our health.

Stay Healthy. Don’t panic.

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